ERBB2 Stable Expression Cell Line (SK-BR-3)

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  • 细胞图0 ERBB2 Stable Expression Cell Line (SK-BR-3)-细胞图0
  • 质粒图0 ERBB2 Stable Expression Cell Line (SK-BR-3)-质粒图0
  • ERBB2 Stable Expression Cell Line (SK-BR-3) ERBB2 Stable Expression Cell Line (SK-BR-3)-产品图
细胞图0 ERBB2 Stable Expression Cell Line (SK-BR-3)-细胞图0
质粒图0 ERBB2 Stable Expression Cell Line (SK-BR-3)-质粒图0
ERBB2 Stable Expression Cell Line (SK-BR-3) ERBB2 Stable Expression Cell Line (SK-BR-3)-产品图
ERBB2 Stable Expression Cell Line (SK-BR-3) Copy Product Info
Catalog#： YOE-L069
Size： 1*10^6
Culture method： 90%McCOY's 5A+10%FBS
STR Report
Datasheet (Use Instruction)
  • 细胞图0 ERBB2 Stable Expression Cell Line (SK-BR-3)-细胞图0
  • 质粒图0 ERBB2 Stable Expression Cell Line (SK-BR-3)-质粒图0
  • ERBB2 Stable Expression Cell Line (SK-BR-3) ERBB2 Stable Expression Cell Line (SK-BR-3)-产品图
ERBB2 Stable Expression Cell Line (SK-BR-3) Copy Product Info
Catalog#： YOE-L069
Size： 1*10^6
Culture method： 90%McCOY's 5A+10%FBS
Datasheet (Use Instruction)

Detailed Product Information

Cell Info

Catalog YOE-L069 Transcript NM_004448.4
Cell name ERBB2 Stable Expression Cell Line (SK-BR-3) Species Human
Gene Name ERBB2 Passage ratio 1:2~1:3
Cell Morphology Epithelial-like, adherent Antibiotic Concentration Puro=1μg/ml
Culture method 90%McCOY's 5A+10%FBS Mycoplasma test negative
Catalog
YOE-L069
Cell name
ERBB2 Stable Expression Cell Line (SK-BR-3)
Gene Name
ERBB2
Cell Morphology
Epithelial-like, adherent
Passage ratio
1:2~1:3
Transcript
NM_004448.4
Species
Human
Antibiotic Concentration
Puro=1μg/ml
Mycoplasma test
negative
Culture method
90%McCOY's 5A+10%FBS

Product Description

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
Gene Expression Validation
No. Sample hERBB2-3CтMean β-h_actinCтMean ΔCтMean ΔΔCт Expression Rate
1 ERBB2 Stable Expression Cell Line (SK-BR-3) 28.292 15.241 13.051 -4.457 21.963
2 SK-BR-3_Ctrl(Puro) 32.565 15.057 17.508 0.000 1.000
STR Profile
Download STR Report
Loci STR Info (Sample Cell)
Sample Cell Line:SK-BR-3		 STR Info (Cell bank)
Cell Line:SK-BR-3
Allele1Allele2Allele3Allele1Allele2Allele3
D5S818 912912
D13S317 11121112
D7S820 99912
D16S539 9999
VWA 17171717
TH01 8989
AMEL XXXX
TPOX 811811
CSF1PO 12121212
D12S391 1820
FGA 2020
D2S1338 2025
D21S11 3030.2
D18S51 1013
D8S1179 1212
D3S1358 1717
D6S1043 1119
PENTAE 1011
D19S433 1414
PENTAD 912
D1S1656 1117.3
* STR authentication data of this cell line matches with that of cell lines sourced from ATCC, DSMZ, JCRB, and RIKEN databases.
Conclusion: The STR identification of this cell is correct.

Product Advantage

  • icon
    High expression
    Exclusive cell selection technique, ensuing high expression, RT-qPCR validation data provided.
  • icon
    Good stability
    Stable gene copy number, low passage, can be stably passaged for more than 20 passages.
  • icon
    Strict QC
    Strict quality control, ensuing no bacterial and mycoplasma contamination, STR authentication and cell post-thawing viability test passed; High standard delivery.
Related Resources: Red Cotton Gene-editing System | ATCC | DSMZ | ECAZZ | Cellosaurus | CCTCC | NCBI
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